Dengue Fever: A Case Study

Ananyaa Srivastava

doi:10.54060/pcc.2023.10

Authors

Ananyaa Srivastava Amity Institute of Pharmacy, Amity University Uttar Pradesh, Lucknow, India

DOI:

https://doi.org/10.54060/pcc.2023.10

Keywords:

Dengue hermorrhagic fever, Flavivirus, Vetor-borne disease

Abstract

Dengue is a pandemic that is brought on by the Dengue Virus (DENV), which is a single-stranded RNA (ribonucleic acid) virus. Dengue is also brought on by the bite of species in the Aedes family. Dengue, which is caused by the Dengue Virus, is the most common arboviral illness in the world and is a member of the Flaviviridae family. I present a study based on Dengue as a pandemic which outbreak on City Hospital of Delhi in the year 2010. Examining the clinical characteristics of dengue posi-tive cases, the prevalence of dengue diagnosis among patients with suspected dengue, and the effects of the aforemen-tioned on the environment and infectious illnesses. 4480 blood samples from clinically probable dengue fever patients were used in an enzyme-linked immunosorbent test (ELISA) to find dengue virus-specific IgM antibody protection. On 55 samples of C6/36 cell monolayers, virus isolation was carried out. The patient's application or the doctor might provide medical and public information about the patient. Results: Of the 4,480 blood samples tested, 1,800 blood samples (40.17%) were de-tected to be positive for the DENV with particular antibodies known as IgM antibodies. The most common group of single species of microorganism detected was DENV type 2. The conditions which were profusely detected were thrombocytopenia in which the blood platelet count observed is low and along with this Myalgia was also detected in which pain in the muscles is observed. In 32.4% and 17.9% of the 1,800-dengue fever IgM positive patients, respectively, low platelet count (thrombo-cytopenia) and muscle discomfort (myalgia) were noted. Together, these conditions accounted for 3% of the cases. Addition-ally, dengue hemorrhagic fever (DHF), which affects 10.3% of the 1,800 persons, has a fatality rate of 0.08%. Conclusions: Increased reporting due to changes in disease outbreaks, unprecedented rainfall, major infrastructure developments and improved medical facilities contributed to the shortage of dengue patients in 2010.

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